There are twelve houses in a horoscope, each one relating to certain aspects of human life, certain relationship, and certain part of the body. For the convenience of the readers, I would mention in brief each one of them. 

1st  Personality, health, character, complexion etc
2nd  Family, eyes, Speech, income etc
3rd  Coborns, endeavour, struggle etc
4th  Domestic bliss, conveyance,immovable propery, mother
5th  Children, purva-punya, education
6th  Illness, debts, litigation etc
7th  Spouse, marriage partnership, marital bliss, travel, business, partnership etc
8th  Longevity, suddenness of events, obstacles, inheritance etc
9th  Religion, spirituality, father, fate etc
10th  Profession, Occupation, Nature of work etc
11th  House of gains, unearned profits like profit on shares, from properties etc.
12th  Bed comforts foreign travel, imprisonment,expenditure , hospitalization etc.


You will observe from above that houses which are intimately connected with the self and the the houses which relate to aspects of marriage have been earmarked for mangal dosh. Pl see above; the 1st house deals entirely with one's personality and health in general. The 2nd house is called kutumbh sthan or house of family, the fourth is sukh sthan or house of comforts, seventh that of spouse and marital bliss, the eighth house relates to age and longevity and the 12th to bed comforts.

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